Score: Seddon-Sunderland classification

Use: Nerve injury

Grade 1: Neuropraxia

  • Conduction disruption with intact axon and preserved supportive structures.
  • Prognosis: normally full recovery in days-weeks without surgical intervention
  • Grade 2: Axonotmesis

  • Disrupted axon with intact endoneurium; Wallerian degeneration takes place after 1-2 weeks
  • Prognosis: variable recovery, worse prognosis for proximal injuries and injuries who do not successfully re-implant in the muscle within 18 months
  • Grade 3: Neurotmesis with preservation of perineurium

    Neurotmesis refers to disruption of supporting structures

  • Endoneurium is disrupted
  • Prognosis: 60-80% recovery
  • Grade 4: Neurotmesis with preservation of epineurium

  • Prognosis: nerve grafting is required
  • Grade 5: Neurotmesis with complete transection of nerve trunk

  • Prognosis: bypass / jump grafting is required
  • Reference

    http://wiki.cns.org/wiki/index.php/Injury,_Classification